With the development of the principle and approach of sequence stratigraphy. It could be used in all lypes of strata including marine, non-marine and mixed marine strata. The enhancement of stratigraphic correlation results that sequence stratigraphy can contribute directly to all stages of the exploration and development. Based on the principle of sequence stratigraphy, this article give the sequence stratigraphy framework and reservoir prediction of Paleogene in Bonan uplift, using drilling well, seismic data, core and other data. According to logs data of the region, 20 short-term base-level cycles (SSC and 6 mediate-term base-level cycles(MSC) could he identified in studying region. There are three types of SSC which are low accommodation, middle accommodation and high accommodation and three types of MSC which are progradalion-retrogradation symmetric,progra-dation-retrogradation asymmetric and progradation-ret-rogradation extreme-asymmetric cycles in these cycles.