Permeability synthesis is often used in reservoir-engineering research such as calculating oil reserve，making oilfield development plan and simulating reservoir numerically, which includes permeability synthesis of different vertical formations and that of different permeability zone along fluids conducting directions．Illumed by the Tenth Five-Year Plan research program，with mathematical methods，according to practical oil geology and exploitation research，this article deduced formulas of the two types of permeability synthesis and verified them by means of experimental data.